Thrombotic thrombocytopenic purpura associated with cerebral SLE.

A case of thrombotic thrombocytopenic purpura in a patient with a recent flare of cerebral lupus is presented. The patient presented with neurologic symptoms, pyrexia, thrombocytopenia and leucocytosis. Following initial investigation, imaging of brain and negative microbiology, a diagnosis of cerebral lupus was made and appropriately treated. After a stable period oftwo weeks, deterioration in clinical status, haematology and renal indices, a diagnosis of thrombotic thrombocytopenic purpura (TTP) was made and treated. The two diagnoses presenting together are briefly discussed.